Reduced expression of β-catenin inhibitor Chibby in colon carcinoma cell lines
نویسندگان
چکیده
AIM: To analyse the Chibby expression and its function in colon carcinoma cell lines and colorectal carcinoma
منابع مشابه
Downregulation of nuclear and cytoplasmic Chibby is associated with advanced cervical cancer
Chibby has been identified as a putative tumor suppressor and antagonist to β-catenin, thereby controlling the Wnt signaling pathway. Chibby is typically downregulated in numerous types of cancer and may be associated with tumorigenesis. The present study aimed at clarifying the following: i) Whether Chibby antagonizes β-catenin in cervical cancer; ii) whether Chibby and β-catenin mRNA expressi...
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